At NCCAT and NYSBC we outreach to the community to provide first-hand exposure to microscopy techniques and disseminate information on how we as structural biologists understand molecular machines (biological complexes that carry out multiple functions within our cells).
What is cryo-electron microscopy?
How does cryoEM help biomedical research?
Public Health Relevance
The structure of a molecule reveals important information about how it functions and can help scientists identify potential new therapeutic targets for vaccines and drugs to combat diseases and conditions. Cryo-electron microscopy (cryo-EM) is a method used to image frozen biological molecules, such as proteins and nucleic acids, without the need for structure-altering dyes or crystallization. Not only can cryo-EM image molecules in their natural shapes, but it can obtain structures of molecules that were impossible using other methods like X-ray crystallography. Recent advances in cryo-EM methods and technology have greatly extended its resolution and the amount of information it can provide about viruses, proteins, and other important biomolecules.
Helping teachers learn about the advanced techniques of structural biology at NYSBC including NMR Spectroscopy, X-ray crystallography, cryo-electron microscopy. Educators have the opportunity to see the equipment first-hand.
The Hugo Boss Prize 2016 winner Anicka Yi’s Life Is Cheap exhibit opening reception was held on Thursday, April 20, 2017. For their invitation, they used a scanning electron microscope (SEM) image of an ant taken at NYSBC.