CryoEM Current Practices Webinar 07/29/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday July 29, 2021 at 12 PM eastern / 9 AM pacific time James Chen, Ph.D. & Brandon Malone from the Laboratory of Molecular Biophysics, The Rockefeller University will present: CoV-er all the bases - Structural perspectives of SARS-CoV-2 RNA synthesis Talk Abstract:  The COVID-19 pandemic has claimed millions of lives and devastated the world economy. Garnering insights into the replication cycle of the causative agent, SARS-CoV-2, will aid the development of therapeutics. SARS-CoV-2 possesses one of the largest viral RNA genomes [...]

CryoEM Current Practices Webinar 06/24/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday June 24, 2021 at 12 PM eastern / 9 AM pacific time Dr. Aashish Manglik, Assistant Professor, Depts. of Pharmaceutical Chemistry & Anesthesia and Perioperative Care University of California, San Francisco will present: Solving molecular puzzles in GPCR signaling with cryo-EM Talk Abstract: Cryo-EM has revolutionized structural studies of G protein-coupled receptors over the past few years. More facile structure determination of active GPCRs has enabled the field to understand the molecular basis of receptor function at an unprecedented pace. I [...]

CryoEM Current Practices Webinar 05/27/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday May 27, 2021 at 12 PM eastern / 9 AM pacific time Nicolas Coudray, Senior Scientist, Bhabha/Ekiert Lab New York Univerity School of Medicine will present: Behind the scenes: CryoEM of E. coli lipid transporters Talk Abstract: The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer composed of LPS in the outer leaflet and phospholipids in the inner leaflet. It constitutes a robust barrier for the cell, often making bacteria resistant to antibiotics that are unable to cross this [...]

NCCAT roundtables – 2021 edition

Come hang out in our virtual conference room and chat about CryoEM. Starting at the end of April, every other Tuesday afternoon at 3:30 PM eastern time we pick up a new topic. Over the course of the spring and summer we will span many aspects of a typical CryoEM workflow. You don't need to come all the way to New York City to pull up a seat with our local experts, ask your own questions and learn something new. You do need to register to get a zoom link, and bring your own snacks, if needed. All are welcome to attend.  Dates and topics     Register here

CryoEM Current Practices Webinar 04/29/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday April 29, 2021 at 12 PM eastern / 9 AM pacific time Dr. Rahul Jaiswal, Instructor, Virginia Commonwealth University School of Medicine will talk about his work on Cryo-EM studies of a malleable oligomeric SF3 helicase Talk Abstract: The adeno-associated virus (AAV) non-structural Rep proteins catalyze all the DNA transactions required for virus viability including, DNA replication, transcription regulation, genome packaging, and during a latent phase, site-specific integration. Rep proteins contain two multifunctional domains: An Origin Binding Domain (OBD) and a SF3 [...]