Single-Particle-Analysis Short Course, in person at NCCAT, March 14-18, 2022. Apply now!

NCCAT is pleased to announce we are accepting applications for our short-course in Single-Particle-Analysis on March 14-18, 2022. The applications deadline is January 1, 2022 at 5pm ET. This 1-week in-person short course will be an immersive and intensive experience in the art and science of cryoEM held at the Simons Electron Microscopy Center in NYC. The mornings offer lectures and stimulating round table discussions. The afternoons provide hands-on practicals to reinforce fundamental concepts and topics covered earlier in the day. For information and to apply please visit the NCCAT Short Course Information Page.

CryoEM Current Practices Webinar 12/09/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday December 9, 2021 at 12 PM eastern / 9 AM pacific time Tarjani Thaker PhD, Scientist in the Tomasiak Lab at the University of Arizona will present Determining structural mechanisms of allosteric regulation in ABCC family transporters using a remote cryo-EM pipeline Talk Abstract: The democratization of cryo‐EM has rapidly advanced thanks to the emergence of cryo‐EM centers, making it possible for institutions lacking the infrastructure to pursue structural investigations by cryo‐EM. Using the tools and expertise available at PNCC, our group at [...]

AMA Information Session

We recently expanded our access categories and our user base has grown since we started in 2018. We are now welcoming our users back on site. We would love to see you attend our information session on November 18th, 2021 at 1:00 pm EST. Please register here: https://www.surveymonkey.com/r/NCCAT-AMA

CryoEM Current Practices Webinar 10/28/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday October 28, 2021 at 12 PM eastern / 9 AM pacific time Helen Donelick, PhD candidate in the Bass and Shen Labs, Department of Biochemistry, University of Utah will present Structural determination of the Dicer-2•R2D2 complex Talk Abstract: The ability to fight a viral infection is essential for all organisms. Drosophila melanogaster utilizes RNA interference for the antiviral response. Here, the protein, Dicer-2, is used for small interfering RNA (siRNA) biogenesis and passing one strand of the siRNA into Argonaute-2 to form the [...]

CryoEM Current Practices Webinar 09/30/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday September 30, 2021 at 12 PM eastern / 9 AM pacific time Christopher Koo, PhD candidate in the Interdisciplinary Biological Sciences Program (IBiS), Rosenzweig Lab, Depts. of Molecular Biosciences and Chemistry, Northwestern University will present CryoEM studies of a methane-oxidizing enzyme in the lipid bilayer Talk Abstract: CryoEM has revolutionized structural studies of membrane proteins over the last decade. Combined with membrane mimetics such as lipid nanodiscs, cryoEM allows for detergent-free structural determination of membrane proteins within a lipid bilayer more [...]