CryoEM Current Practices Webinar 04/29/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday April 29, 2021 at 12 PM eastern / 9 AM pacific time Dr. Rahul Jaiswal, Instructor, Virginia Commonwealth University School of Medicine will talk about his work on Cryo-EM studies of a malleable oligomeric SF3 helicase Talk Abstract: The adeno-associated virus (AAV) non-structural Rep proteins catalyze all the DNA transactions required for virus viability including, DNA replication, transcription regulation, genome packaging, and during a latent phase, site-specific integration. Rep proteins contain two multifunctional domains: An Origin Binding Domain (OBD) and a SF3 [...]

CryoEM Current Practices Webinar 03/25/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday March 25, 2021 at 12 PM eastern / 9 AM pacific time Dr. Richard H. Ebright, Board of Governors Professor of Chemistry and Chemical Biology, Rutgers University will talk about his work on the Structural basis of transcription-translation coupling Talk Abstract:  In bacteria, transcription and translation are coupled processes, in which movement of RNA polymerase (RNAP) synthesizing mRNA is coordinated with movement of the first ribosome translating mRNA. Coupling is modulated by the transcription factors NusG--which is thought to bridge RNAP and [...]

CryoEM Current Practices Webinar 02/25/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday February 25, 2021 at 12 PM eastern / 9 AM pacific time Bobby Hollingsworth, Graduate Student, Hao Wu Lab, Harvard Medical School will talk about his work on Workflow tricks for determining cryo-EM structures of filaments, small proteins, and protein complexes Talk Abstract: Moving through a cryo-EM project can be daunting, and issues might arise at every step of the process from sample preparation to preferential orientation on cryo-EM grids and molecular modelling. Here, I will briefly discuss our recent structural advances of [...]

CryoEM Current Practices Webinar 01/28/2021

The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on Thursday January 28, 2021 at 12 PM eastern / 9 AM pacific time Dr. Michael A. Cianfrocco, Assistant Professor, Department of Biological Chemistry, University of Michigan will talk about his work on Cloud computing tools for cryoEM Talk Abstract: Single-particle cryoEM has become a go-to technique for structural biologists across a wide range of biological disciplines. Continued investments in national and regional cryoEM instrumentation now provides access for increased numbers of labs. Despite these improvements, access to data processing resources remains a [...]

Happy Holidays

Wishing our extended CryoEM family a healthy, happy holiday season. May the coming year be full of Krios time and beautiful data!