Carlos and Vishaka’s Story

Vishaka Santosh finally arrived at the New York Structural Biology Center (NYSBC) on Tuesday, February 19 just a few minutes past her Krios loading time. Truly it was remarkable she made it at all, the previous 24 hours had been a lengthy expedition. Vishaka is a post-doctoral fellow in Dr. Carlos Escalante’s lab in the Physiology and Biophysics department at Virginia Commonwealth University (VCU). They applied to the first cycle in NCCAT’s General User Proposal (GUP) program, which supports single particle cryoEM data collection on one of the Titan Krios instruments at NYSBC. Dr. Escalante’s lab at VCU focuses on the study of the structure and function of proteins and protein-DNA complexes central to transcriptional activation and the initiation of viral DNA [...]

Pramod’s Story

In research science planning an experiment is not unlike chess, it requires a lot of carful advanced planning along with the ability to improvise when something develops differently from what you were expecting. At least that how molecular biologist Pramod Kumar at University of Illinois views its. Pramod was actually a chess champion when he was an undergrad back in India, and the similarities of patience and preparation needed for each is not lost on him. Now, Pramod is a post-doctoral researcher in Professor Claudio Grosman’s lab at University of Illinois at Urbana Champaign (UIUC). There his studies are focused on ion-channel structure. As early as high school Pramod has been interested in membrane proteins and intrigued by their selective permeabilities [...]

John and Jenna’s Story

It’s morning in Harlem and John and Jenna are in search of breakfast. I guess no one told them about how good New York bagels are since they end up at Dunkin Donuts and a nearby juice bar. They’ve come to New York from San Francisco because they have been awarded Krios time from NCCAT at NYSBC, something that eluded them back in San Francisco. Although the University of California San Francisco (UCSF) has two Krios microscopes, getting time on them is very difficult and is a significant bottleneck in their research program. John Lee is a post doc in James Fraser’s lab in the department of Bioengineering and Therapeutic Sciences at UCSF.  He is learning CryoEM, after making the jump [...]

ISMMS Research Resources Fair

Meet us at the ISMMS Research Resources Fair to get the word out about the NIH Transformative High Resolution Cryo-Electron Microscopy Program.

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