• 1 week.

  • Morning lectures.

  • Afternoon practicals.

  • March 16-20, 2026.

  • students/postdocs $375.
    staff/PIs/professionals $450.
    industry $625.

  • Room and board NOT included.

Apply here.

Accepted applicants will be notified by January 2026.

For more information email nccatuseroffice [at] nysbc.org

Full Agenda

coming soon.

Speaker BIOs

coming soon.

Visitor's Guide

Learn about West Harlem.

Additional Lodging

Places to stay.

Short-course FAQ

FAQ.
see the 2024 shortcourse

Single Particle Short Course
March 16-20, 2026

NCCAT will offer a 1 week workshop focused on the theory and practice of single-particle analysis. The mornings are filled with lectures and stimulating round table discussions. The afternoons provide hands-on practicals to reinforce fundamental concepts and topics covered earlier in the day.

Short-course Agenda

Monday, March 16, 2026
Session Type Lecturer Topic
Morning Lecture 1 – Keynote Joachim Frank (Columbia University) Intro and overview of SPA
Morning Roundtable 1 students Flashtalks from students
Afternoon Lecture 2 SEMC staff Sample preparation for biological samples
Afternoon Practical 1 SEMC staff cryoEM sample prep and grid prep stations

Tuesday, March 17, 2026
Session Type Lecturer Topic
Morning Lecture 3 SEMC staff Microscopes and tools of the trade
Afternoon Roundtable 2 SEMC staff Making use of local facilities and national centers
Afternoon Practical 2 SEMC staff Plunge freezing & TEM stations

Wednesday, March 18, 2026
Session Type Lecturer Topic
Morning Lecture 4a Fred Sigworth (Yale University) Algorithms and foundational math PartI:
derivation/explanation of the CTF, FTs.
Morning Lecture 4b Fred Sigworth (Yale University) Algorithms and foundational math PartII:
reconstruction, classification, maximum likelihood.
Morning Lecture 5 David Jeruzalmi (City Univerisity of New York) Data Analysis and reconstruction workflow
Lunch Roundtable 3 Fred Sigworth & David Jeruzalmi Current and new algorithms to deal with SPA reconstruction
Afternoon Practical 3 SEMC staff Processing using cryoSPARC

Thursday, March 19, 2026
Session Type Lecturer Topic
Morning Lecture 6 Rich Hite (Memorial Sloan Kettering Cancer Center) Interpretation and Limitations of SPA
Morning Lecture 7 Andres Leschziner Applications of cryoEM in the life sciences
Lunch Roundtable 4 Rich Hite & others EM challenges and new frontiers
Afternoon Practical 4 SEMC staff Autoloader TEMs and Krios data collection at a national center
Dinner all instructors Group dinner

Friday, March 20, 2026
Session Type Lecturer Topic
Morning Lecture 9 Oli Clarke (Columbia University) Fitting Atomic Models
Morning Lecture 10 Justin Flatt (RSCB/PDB) Streamlining OneDep Depositions of Multiple Related 3DEM Entries
Morning Roundtable 5 Oli Clarke & Justin Flatt Making cryoEM information accessible to the community.
Afternoon Practical 5 Oli Clarke Coot and model building

This workshop is limited up to 16 attendees and accepted applicants will receive instructions for payment of the course fee.

Apply here.

We will reach out to participants by end of January to the beginning of February. For further inquires please email the NCCAT User Office.

Yes. This will be an in-person on-site workshop.

Yes. Parts of the workshop will be recorded. We will post all learning materials on our website.

Accepted participants will be charged for this course. Travel, food and housing costs are not covered. Instructions will follow after acceptance.

students/postdocs $375.
staff/PIs/professionals $450.
industry $625.

If participants cancel or withdraw from the short course:

  • 1 month ahead of the workshop a refund of up to 66% minus a processing fee will be returned,
  • 2 weeks ahead of the workshop a refund of up to 50% minus a processing fee will be returned,
  • 1 week ahead of the workshop there will not be any refunds.