The next installment of the monthly methods-focused webinar series hosted by the National Center for CryoEM Access and Training (NCCAT), along with the Pacific Northwest Center for CryoEM (PNCC), and the Stanford-SLAC CryoEM Center (S2C2) will be held on
Thursday September 30, 2021 at 12 PM eastern / 9 AM pacific time
Christopher Koo, PhD candidate in the Interdisciplinary Biological Sciences Program (IBiS), Rosenzweig Lab, Depts. of Molecular Biosciences and Chemistry, Northwestern University will present CryoEM studies of a methane-oxidizing enzyme in the lipid bilayer
Talk Abstract: CryoEM has revolutionized structural studies of membrane proteins over the last decade. Combined with membrane mimetics such as lipid nanodiscs, cryoEM allows for detergent-free structural determination of membrane proteins within a lipid bilayer more closely matching the native environment. I will discuss the process of embedding a methane-oxidizing enzyme in lipid nanodiscs and how structure determination within the bilayer gives new insight into the function of the enzyme.