TP Application Instructions2018-10-17T02:00:46+00:00

TP Application instructions

Application requirements.

Training Proposal
There is a specific application for embedded user or facility management training. There are two (2) types of training proposal applications:

TP1: Embedded Training
TP2: Facility Manager Training

The TP1 program is embedded training is to train a scientist to become an independent cryoEM researcher. NCCAT staff will assist with access and trainings over a ~ 3 month intensive immersion program. The TP2 program is extended training to individuals who are responsible for managing, leading or training at their own facilities; these individuals will have considerably amplified impact when they return to their home institution.

Applications will be limited to one page of text and one page of supporting data and figures. Key personnel named in the application must also submit an NIH Biosketch (https://grants.nih.gov/grants/forms/biosketch.htm). .

Early access training program.

This initial cycle will support TP2s (for cryoEM facility management and operations) and a limited number of TP1s (for embedded training). We offer extended training to individuals who are responsible for managing, leading or training at their own facilities. They will be intimately incorporated into the daily operations of the Center, participating in every aspect of day-to-day operations and management. The goal will be to expose these individuals to all the procedures and protocols of the Center and provide them with ample opportunity for extensive discussion of best practices with the professional staff. The expected time frame is 1 week to 1 month.

Accepted NCCAT users (and their PI’s if applicable) are required to sign a written agreement that they will comply with all NIH data sharing, reporting and publication policies. The written agreement will also outline other requirements and policies for NCCAT access so as to manage expectations as transparently as possible.

Application process

A training program will encompass a full range of expectations, from the basics required to ensure that users produce valid structures, through more detailed training for users seeking independence, to fully embedded researchers who will be expected to graduate to running their own cryoEM research laboratories.

The training goals at NCCAT will be to produce as many functional cryoEM practitioners as possible at a variety of levels. These levels will vary from fully independent researchers capable of running their own facilities at one end of the spectrum, to those, at the other end, who use the center staff for specimen preparation and data acquisition and only require training in evaluating their data, processing, and validating their final structures. These diverse training goals will be greatly assisted and accelerated by two important aspects: (i) a very high level of automation at NCCAT; and (ii) very rich on-line training resources available at NCCAT as well as in the public domain.

Users applications are scored in the following categories: (i) training goals; (ii) training plan; (iii) resources requested; (iv) user EM background and history; (v) geographical demographics. The URC will score these aspects on a scale of 1-5 and also have the option to provide additional comments.

A request for training proposal will expire in three (3) cycles or when the requested amount of time recommended by peer review has been used, whichever comes first. After that point users will have to submit a new project to submit additional request for access applications/proposals against. The content of proposal will be kept confidential by the reviewer or relevant committees. A user may specify individuals that pose a potential conflict and exclude them from the external review committee.

Categories for review

The user review committee (URC) will score with respect to five (5) different categories.
(i) training goals: areas and scope for training;
(ii) training plan: specific objectives and milestones for the proposed training, and provide details on the potential growth in the EM areas outlined;
(iii) resources requested: what period of time is requested for the training period and instrumentation that may be required;
(iv) user EM background and history: brief history with current expertise level and familiarity with equipment;
(v) geographical demographics: proximity to potential training opportunities and cryoEM practitioners in your area, and describe the impact if successful.

Note: Geographical diversity, need for access by under-served or under-represented institutions, the extent of requested support, and other options available to the users or the trainees, will be taken into account in setting priorities.

These scores will be combined and averaged for a final proposal score from 1 (excellent) to 5 (poor).

Possible scores

Scores are on a scale from 1 (excellent) to 5 (poor).

Score Title Description
1 Excellent Highly innovative training potential with great scientific or technological importance. Access to NCCAT is integral to the success of the work.
2 Good High impact training with the potential for making an important contribution to a specific field, scientific discipline, or technical development project. Use of NCCAT resources is important to a successful outcome of the work.
3 Satisfactory Training likely to produce some benefit or incremental technological advance in understanding EM. The work will benefit from access to NCCAT.
4 Needs improvement Training may not significantly impact a specific field, scientific discipline, or technological area. Proposed training would also be able to be completed in other facilities including the home institution of the user.
5 Poor / Unsatisfactory Not well-planned or not feasible. The need for use or traveling to a national center is not clear.
NR No Review Insufficient information to base a review.
Note: Scored proposals that have not been assigned time will automatically be forwarded to the next cycle with an improvement of 0.2. Proposals will be forwarded for a maximum of two (2) times for a maximum improvement of 0.4.